A senescence stress secretome is a hallmark of therapy-related myeloid neoplasm stromal tissue occurring soon after cytotoxic exposure

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  • who: Monika M. Kutyna from the (UNIVERSITY) have published the article: A senescence stress secretome is a hallmark of therapy-related myeloid neoplasm stromal tissue occurring soon after cytotoxic exposure, in the Journal: (JOURNAL) of 29/08/2022
  • what: One limitation of the study is that the serial BMSC studies (Fig 8), while convincingly show evidence of time-dependent causality before and after exposure to CT, were obtained exclusively Leukemia 36:2678 - 2689 from patients with multiple myeloma. The study provides comprehensive phenotypic, functional, and molecular profiling of tMN BMSC compared to carefully curated samples . . .

     

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