A short amphipathic alpha helix in scavenger receptor bi facilitates bidirectional hdl-cholesterol transport

HIGHLIGHTS

  • who: Sarah C. May from the Department of Medicine, Division of Endocrinology and Molecular Medicine, Medical College of Wisconsin, Wisconsin, USA have published the article: A short amphipathic alpha helix in scavenger receptor BI facilitates bidirectional HDL-cholesterol transport, in the Journal: (JOURNAL)
  • what: Although the authors focus on the impact of SR-BI mutations on cholesterol transport through the SR-BI monomer, it is also possible that multiple SR-BI extracellular domains pack together, forming a hydrophobic channel.
  • future: More research is needed to investigate this potential cholesterol transport pathway. Investigation is . . .

     

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