HIGHLIGHTS
SUMMARY
The loop region contains an antisense recognition domain against a nucleic_acid target, and the absence of a target allows the molecular beacon to self-hybridize at the stem. Compared with other types of nucleic_acid probes (such as constructing DNA double-stranded hybridization system), the structure of the molecular beacon is simple, and one kind of molecular beacon can detect one kind of target in a homogeneous system. The specific binding of T base and Hg2+ led to the conformational change in the molecular beacon aptamer, which enlarged the distance between the fluorescence group and . . .
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