A simple-to-perform ifn-γ mrna gene expression assay on whole blood accurately appraises varicella zoster virus-specific cell-mediated immunity after allogeneic hematopoietic stem cell transplantation

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SUMMARY

    Frontiers in Immunology | www.frontiersin.org July 2022 | Volume 13 | Article 919806 VZV-Specific Cell-Mediated Immunity After HSCT A B C post-transplant care, the implementation of the VZV-specific ifn-g gene_expression assay on whole blood at a lab experienced in the follow-up of allo-HSCT recipients should be relatively easy. Taken together and considering that one quarter of alloHSCT recipients had detectable VZV-specific cell-mediated immunity by the time of study initiation (6 months posttransplant), measuring the VZV-specific ifn-g gene_expression level in whole blood once every trimester . . .

     

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