A simulation study of fet-based nanoelectrodes for active intracellular neural recordings

HIGHLIGHTS

SUMMARY

    In-vitro and in-vivo neuroscience studies to better understand neural-network working principles, experiment the treatment of neurological disorders, and develop reliable and stable human-brain interfaces,, require advanced neural sensors featuring high spatio-temporal resolution, longterm recording, and sensitivity to sub- and supra-threshold potentials with high signal-to-noise ratio (SNR). The cellular membrane is described either as a lossless insulator directly in the TCAD domain compartment with a relative permittivity εr,memb ≈ 11, and a capacitance Cm ≈1 µF/cm2 consistent to those of neurons, or as a lumped capacitor . . .

     

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