HIGHLIGHTS
- who: Christine Boucheron from the (UNIVERSITY) have published the Article: A Single Amino Acid in the DNA Binding Regions of STAT5A and STAT5B Confers Distinct DNA Binding Specificities*, in the Journal: (JOURNAL) of August/14,/1998
SUMMARY
Chimeric STAT5 molecules allowed the authors to identify a region between amino_acid 420 and 545 responsible for the DNA binding specificity. Sequence comparison between STAT5A and STAT5B from different species showed a difference of 5 amino_acids in the region 420 -545 between STAT5A and STAT5B. Substitution of these amino_acids demonstrated that a glycine residue at position . . .
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