HIGHLIGHTS
- who: Christopher P. Cook from the University of California, San Francisco, San Francisco, CA, USA have published the article: A single-cell transcriptional gradient in human cutaneous memory T cells restricts Th17/Tc17 identity, in the Journal: (JOURNAL) of August/16,/2022
- what: The authors investigate this regulatory pattern primarily in the Trm1 subpopulation, in which Th17/Tc17 cytokines are expressed in psoriasis samples and can be studied directly, but other inflammatory markers negatively correlate with ZFP36L2-deficiency in other T_cell classes . The authors propose that in psoriatic lesion development, general, exogenous inflammatory insults suppress . . .
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