A single chain fragment variant binding misfolded alpha-synuclein exhibits neuroprotective and antigen-specific anti-inflammatory properties

HIGHLIGHTS

  • who: Michael Fassler and collaborators from the (UNIVERSITY) have published the research work: A Single Chain Fragment Variant Binding Misfolded Alpha-Synuclein Exhibits Neuroprotective and Antigen-Specific Anti-Inflammatory Properties, in the Journal: Cells 2022, 3822 of 15/Oct/2022
  • what: Aiming to overcome some of the limitation of this approach, the authors aimed to select an u03b1Syn binding scFv antibody format and test it in multiple experimental PD in_vivo models. The optimal therapeutic agent would need to address the different triggerHerein, the authors aimed at exploring an agent that was designed to overcome the . . .

     

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