A single episode of cortical spreading depolarization increases mrna levels of proinflammatory cytokines, calcitonin gene-related peptide and pannexin-1 channelsin the cerebral cortex

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  • who: Maria N. Volobueva et al. from the Department of Molecular Neurobiology, Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Butlerova Street A, Moscow, Russia have published the research work: A Single Episode of Cortical Spreading Depolarization Increases mRNA Levels of Proinflammatory Cytokines, Calcitonin Gene-Related Peptide and Pannexin-1 Channelsin the Cerebral Cortex, in the Journal: (JOURNAL) of 21/Dec/2022
  • what: The authors examined whether a single CSD induced in undrugged freely moving animals modifies the expression of key proinflammatory markers (Il1b, TNF, and Il6) and endogenous mediators of nociceptive . . .

     

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