A spatially resolved atlas of the human lung characterizes a gland-associated immune niche

HIGHLIGHTS

  • who: Elo Madissoon from the (UNIVERSITY) have published the research: A spatially resolved atlas of the human lung characterizes a gland-associated immune niche, in the Journal: (JOURNAL) of 26/07/2022
  • what: The authors show that gland epithelial_cells recruit B cells and IgA plasma cells, and promote longevity and antibody secretion locally through expression of CCL28, APRIL and IL-6. By integrating scRNA-seq/snRNA-seq with ST, the authors provide fine-grained resolution of 80 cell types/states in the human lung and airways. The authors provide transcriptomic profiles of human airway 74 . . .

     

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