A stochastic and dynamical view of pluripotency in mouse embryonic stem cells

HIGHLIGHTS

  • who: Yen Ting Lin and colleagues from the Mexico, United States of America, School of Physics and Astronomy, The University of Manchester have published the article: A stochastic and dynamical view of pluripotency in mouse embryonic stem cells, in the Journal: (JOURNAL) of February/16,/2018
  • what: The authors develop a framework for systematically extending Boolean-level network topologies into higher resolution models of networks which explicitly account for the promoter architectures and gene state switching dynamics. The authors show the framework to be useful for disentangling the various contributions that gene switching external signaling . . .

     

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