A strategy for high antibody expression with low anti-drug antibodies using aav9 vectors

HIGHLIGHTS

  • who: April and colleagues from the Genemagic Biosciences, United States University of Pennsylvania, United States have published the paper: A strategy for high antibody expression with low anti-drug antibodies using AAV9 vectors, in the Journal: (JOURNAL)
  • what: The aim of the study was to select a capsid for i.m. administration. The authors compared five AAV capsids for their ability to express an antibody after i.m. administration in rhesus macaques. No power analysis was conducted to determine group size.
  • how: For all the previous studies in rhesus macaques the authors selected . . .

     

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