A streamlined workflow for single-cells genome-wide copy-number profiling by low-pass sequencing of lm-pcr whole-genome amplification products

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  • who: Alberto Ferrarini et al. from the Medical Faculty, University Hospital of the Heinrich- Heine-University Duu0308sseldorf, Duu0308sseldorf, Germany have published the research: A streamlined workflow for single-cells genome-wide copy-number profiling by low-pass sequencing of LM-PCR whole-genome amplification products, in the Journal: PLOS ONE | https://doi.org/10.1371/journal.pone [0193689]. March 1, 2018 of /1371/
  • what: The authors show that the developed method allows one to obtain an unbiased representation of the original DNA template providing a powerful alternative to widely used aCGH to detect CNAs with . . .

     

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