A structural analysis of dna binding by myelin transcription factor 1 double zinc fingers*

HIGHLIGHTS

  • who: Roland Gamsjaeger from the (UNIVERSITY) have published the article: A Structural Analysis of DNA Binding by Myelin Transcription Factor 1 Double Zinc Fingers*, in the Journal: (JOURNAL) of April/30,/2013
  • how: The data showed that F2 and F5 bind with similar affinities (Ka ⬃1 ⫻ 106 M⫺1 under the conditions of the binding experiments) whereas F3 F4 and F6 bind at least 10-fold less tightly (precise affinities were not measured). Mutational Analysis and RDCs Were Used to Evaluate and Refine the Structural Model-Based on the 15N HSQC titration data and a . . .

     

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