A structure-based mechanism for the denaturing action of urea, guanidinium ion and thiocyanate ion

HIGHLIGHTS

• who: Antonella Paladino et al. from the Institute of Biostructures and Bioimaging, CNR, Via Pietro Castellino, Naples, Italy Institute of Molecular Biology and Pathology, CNR c/o Department Chemistry, Sapienza University of Rome have published the research work: A Structure-Based Mechanism for the Denaturing Action of Urea, Guanidinium Ion and Thiocyanate Ion, in the Journal: Biology 2022, 1764 of /2022/
• what: In this context, the authors propose a general mechanistic model in which urea, due to its chemical features, proves to be the chemical agent endowed with the milder denaturing power.
• how . . .
  

   

  

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