A syntenin inhibitor blocks endosomal entry of sars-cov-2 and a panel of rna viruses

HIGHLIGHTS

  • who: Richard Lindqvist and collaborators from the Department of Clinical Microbiology, Umeu00e5 University, Umeu00e5, Universitetsparken, Copenhagen, Denmark have published the paper: A Syntenin Inhibitor Blocks Endosomal Entry of SARS-CoV-2 and a Panel of RNA Viruses, in the Journal: Viruses 2022, 2202 of /2022/
  • what: The authors show that a highly potent and metabolically stable peptide inhibitor that binds to the PDZ1 domain of syntenin inhibits severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection by blocking the endosomal entry of the virus. The authors demonstrate the importance of syntenin for infection of . . .

     

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