HIGHLIGHTS
SUMMARY
Several studies have shown that CASP3 promotes tumour growth by creating a microenvironment that promotes angiogenesis (Feng et_al, 2017; Bernard et_al, 2019). Increased numbers of CD4+ T_cells, CD8+ T_cells, neutrophils, and macrophages in LGG were associated with poorer prognosis. In BLCA, increased numbers of CD4+ T_cells and B cells indicated an improved prognosis, and increased neutrophil infiltration in SKCM and increased CD4+ T_cell infiltration in PAAD and SARC also predicted improved prognosis. From existing studies indicate that DNA methylation levels can be used as biomarkers for the early detection, diagnosis, and prognosis of cancer . . .
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