A systematic study of site-specific galnac-type o-glycosylation modulating proprotein convertase processing*

HIGHLIGHTS

  • who: Katrine Ter-Borch Gram Schjoldager from the (UNIVERSITY) have published the Article: A Systematic Study of Site-specific GalNAc-type O-Glycosylation Modulating Proprotein Convertase Processing*, in the Journal: (JOURNAL) of November/18,/2011
  • what: The authors first used a model system to delineate the sequence range within which site-specific O-glycosylation may affect PC processing in_vitro and ex vivo in cells, JOURNAL OF BIOLOGICAL CHEMISTRY and demonstrate that O-glycans at least ⫾3 residues N- and C-terminal and of the RXXR furin recognition motif may affect processing.

SUMMARY

     

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