A systems-level approach to parental genomic imprinting: the imprinted gene network includes extracellular matrix genes and regulates cell cycle exit and differentiation

HIGHLIGHTS

  • who: from the Institut de Genomique Fonctionnelle, Montpellier, France have published the research work: A systems-level approach to parental genomic imprinting: the imprinted gene network includes extracellular matrix genes and regulates cell cycle exit and differentiation, in the Journal: (JOURNAL)
  • what: The authors show that imprinted genes are coexpressed in a network that is regulated at the transition from proliferation to quiescence and differentiation during fibroblast cell cycle withdrawal, adipogenesis in_vitro, and muscle regeneration in_vivo. This work shows for the first time that they belong to a single gene network. This study identified significantly . . .

     

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