A tensor decomposition-based integrated analysis applicable to multiple gene expression profiles without sample matching

HIGHLIGHTS

SUMMARY

    To determine whether this simple idea can integrate multiple gene_expression profiles lacking sample matching, the authors attempted to integrate datasets 1, 2, and 3. This suggests that TD-based unsupervised FE is a promising method for integrating gene_expression profiles without sample matching. The authors have previously ­ emonstrated11 that integrated analyses of gene_expression profiles between model animals treated by various d drugs and patients were useful to determining which drug compounds are effective against diseases. There, the authors integrated only one disease gene_expression profile with that of the drug treatment. The authors integrated more gene_expression . . .

     

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