A three-dimensional culture system for generating cardiac spheroids composed of cardiomyocytes, endothelial cells, smooth-muscle cells, and cardiac broblasts derived from human induced-pluripotent stem cells

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  • who: July and collaborators from the Ludwig Boltzmann Institute for Traumatology, Austria Stanford University, United States have published the paper: A three-dimensional culture system for generating cardiac spheroids composed of cardiomyocytes, endothelial cells, smooth-muscle cells, and cardiac broblasts derived from human induced-pluripotent stem cells, in the Journal: (JOURNAL)
  • what: For the experiments described in this report, the authors differentiated hiPSCs into CMs, ECs, SMCs, and CFs and then combined the differentiated cells in a 3D culture environment, where they formed spheroids containing all four cardiac-cell types (i.e., cardiac microtissues). The . . .

     

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