HIGHLIGHTS
- who: Corinne Loeuillet et al. from the Institute for Advanced Biosciences (IAB), Team Host-Pathogen Interactions and Immunity to Infection, Centre de Biochimie Structurale (CBS), CNRS, Montpellier, Montpellier, France have published the article: A Tiny Change Makes a Big Difference in the Anti-Parasitic Activities of an HDAC Inhibitor, in the Journal: (JOURNAL)
- what: The authors show that 1-N-hydroxy-4-N[(2-methoxyphenyl)methyl]benzene-1 4-dicarboxamide a 363 isomer does not have antiparasitic potency and has a 13-fold decrease in HDACi activity.
SUMMARY
About one-third . . .
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