HIGHLIGHTS
- who: Min Joung Lee from the Department of Biochemistry, Chungnam National University School of Medicine, Daejeon, Republic of Korea have published the article: A transcriptomic analysis of cerebral microvessels reveals the involvement of Notch1 signaling in endothelial mitochondrial-dysfunction-dependent BBB disruption, in the Journal: (JOURNAL)
- what: This analysis showed that isolated microvessels are composed of ECs with astrocytes and pericytes, and that their composition was not significantly different between WT and KO mice. The authors focused on cerebral microvessels in which ECs showed profound mitochondrial dysfunction, and identified changes in Notch1, PPARGC1A and WNT1 . . .
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