A transfected sialyltransferase that is elevated in breast cancer and localizes to the medial/trans-golgi apparatus inhibits the development of core-2-based o-glycans

HIGHLIGHTS

  • who: Caroline Whitehouse et al. from the Department Children and University of WC A PX, United Kingdom have published the Article: A Transfected Sialyltransferase That Is Elevated in Breast Cancer and Localizes to the medial/trans-Golgi Apparatus Inhibits the Development of core-2-based O-Glycans, in the Journal: (JOURNAL) of June/16,/1997

SUMMARY

    This change in glycosylation pattern has been best documented in breast cancer where the MUC1 mucin (Gendler et_al, 1990) has been shown to carry shorter and less complex O-glycans than the mucin produced by normal cells . . .

     

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