A trkb agonist prodrug prevents bone loss via inhibiting asparagine endopeptidase and increasing osteoprotegerin

HIGHLIGHTS

• who: Jing Xiong from the generated as reported All in vivo experiments were carried out in female mice. All mice were kept under specific pathogen-free conditions in an environmentally controlled clean room with the humidity ranged, % to, % and housed at , °C on a, h/12-h light/ dark cycle. Food and water were provided ad lib. The experiments were conducted according to the NIH animal care guidelines and Emory School of Medicine guidelines. The protocol was reviewed and approved by the Institutional Animal Care and Use Committee (IACUC) at Emory University. All procedures performed in studies . . .
  

   

  

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