A trustworthy mechanochemical route to isocyanides

HIGHLIGHTS

  • who: Francesco Basoccu et al. from the Italy Italy Italy have published the paper: A trustworthy mechanochemical route to isocyanides, in the Journal: (JOURNAL)
  • what: The authors focused the attention on acetic, trifluoroacetic, and isatoic anhydrides to achieve this. The approach for the removal of the unreacted p-tosyl chloride was demonstrated to be the most feasible and eco-friendly compared with the reported techniques, which imply the use of cellulose with a large excess of pyridine and the need for flash chromatography .
  • how: The best results were obtained when a stoichiometric ratio . . .

     

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