A tryptophan metabolite of the microbiota improves neovascularization in diabetic limb ischemia

HIGHLIGHTS

  • who: Jian An and Fei Wang from the Department of Cardiology, Shanxi Hospital, Taiyuan, China Peking University Third Hospital have published the research work: A Tryptophan Metabolite of the Microbiota Improves Neovascularization in Diabetic Limb Ischemia, in the Journal: (JOURNAL)
  • what: The authors used STZ-induced mice and HG (high glucose)-treated ECs to evaluate the role of 3-IAId in modulating diabetic angiogenesis. mice were anesthetized with isoflurane and placed on a heating pad at 37u25e6 C. Limb perfusion was detected on Days 1, 3, 7, 14 and 21 after ligation.
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