A twenty-year journey exploring coumarin-based derivatives as bioactive molecules

HIGHLIGHTS

• who: October et al. from the University of Belgrade, Serbia Universitu00e9 d`Orlu00e9ans, France have published the research: A twenty-year journey exploring coumarin-based derivatives as bioactive molecules, in the Journal: (JOURNAL)
• what: The interest toward coumarin derivatives by the Carotti`s group began in the early 2000 s from a project aimed at generating ligand-based models of neurotoxicity of MAO substrates, using the classical Hansch quantitative structureactivity relationships (QSARs) and comparative molecular field analysis (CoMFA) (Youdim et_al, 2006).
• how: The best results were obtained by 4-imidazolyl coumarin derivatives (Leonetti . . .
  

   

  

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