HIGHLIGHTS
- who: Liu et_al Retrovirology and collaborators from the (UNIVERSITY) have published the research work: A whole genome screen for HIV restriction factors, in the Journal: (JOURNAL)
- what: The authors focused on the PAF1 complex which has been previously implicated in gene transcription cell cycle control and mRNA surveillance. PAF1 is expressed in primary monocytes macrophages and T-lymphocytes and the authors demonstrate strong activity in MonoMac1 a monocyte cell line. The authors propose that the PAF1c establishes an anti-viral state to prevent infection by incoming retroviruses. The authors report here the results of an . . .
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