A yeast-based screening unravels potential therapeutic molecules for mitochondrial diseases associated with dominant ant1 mutations

HIGHLIGHTS

• who: Giulia di Punzio and collaborators from the Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma have published the research: A Yeast-Based Screening Unravels Potential Therapeutic Molecules for Mitochondrial Diseases Associated with Dominant ANT1 Mutations, in the Journal: (JOURNAL) of 19/03/2021
• how: For these analyses the authors used the lipophilic green-fluorescent dye 33Pdihexyloxacarbocyanine iodide (DiOC6 ) whose uptake by mitochondria and consequently its fluorescence emission are modulated by the MMP. This result indicated thatthe the drugsgrowth exerted their activity was present in other indicated that the drugs exerted their . . .
  

   

  

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