Aav-8 and aav-9 vectors cooperate with serum proteins differently than aav-1 and aav-6

HIGHLIGHTS

  • who: Jérôme Denard from the Department Source de la Bièvre, Montigny-le-Bretonneux, France have published the research work: AAV-8 and AAV-9 Vectors Cooperate with Serum Proteins Differently Than AAV-1 and AAV-6, in the Journal: (JOURNAL) of 10/09/2018
  • what: The authors show that in contrast to rAAV-1 and rAAV-6 there was a substantial similarity in protein binding patterns between mouse and human sera for these vector serotypes. The authors have identified serum proteins interacting with AAV-8 and -9, two serotypes often used in . . .

     

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