Abca1 in adipocytes regulates adipose tissue lipid content, glucose tolerance, and insulin sensitivity[s]

HIGHLIGHTS

• who: Willeke de Haan from the CentreUniversity of British Columbia, Vancouver, BC, Canada have published the research work: ABCA1 in adipocytes regulates adipose tissue lipid content, glucose tolerance, and insulin sensitivity[S], in the Journal: (JOURNAL) of 30/Oct/2013
• what: The authors demonstrate that adipose ABCA1 deficiency increases cholesterol and TG storage in adipocytes and reduces adiponectin, visfatin, and glut-4 expression. The authors directly investigated how adipocyte ABCA1 affects adipose lipid content and adipose function using a mouse model specifically lacking ABCA1 in adipocytes. The authors demonstrated significantly increased intracellular cholesterol levels in . . .
  

   

  

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