HIGHLIGHTS
- who: Barkha Ramnani and collaborators from the Department of Biological Sciences, University of Toledo, West Bancroft Street, Toledo, OH, USA have published the article: ABCE1 Regulates RNase L-Induced Autophagy during Viral Infections, in the Journal: Viruses 2021, 315 of /2021/
- what: The authors show that the ATP-binding cassette E1 (ABCE1) transporter identified as an inhibitor of regulates activity and L-induced autophagy during viral infections. knockdown cells show increased activity when activated by 2-5A. The authors show that ABCE1 inhibits RNase L activity; cells with reduced ABCE1 levels transfected with 2-5A . . .
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