Aberrant epigenomic modulation of glucocorticoid receptor gene (nr3c1) in early life stress and major depressive disorder correlation: systematic review and quantitative evidence synthesis

HIGHLIGHTS

  • who: Laurens Holmes Jr. et al. from the Biological Sciences Department, University of Delaware, Newark, DE, USA have published the article: Aberrant Epigenomic Modulation of Glucocorticoid Receptor Gene (NR3C1) in Early Life Stress and Major Depressive Disorder Correlation: Systematic Review and Quantitative Evidence Synthesis, in the Journal: (JOURNAL)
  • what: This study aimed to: (a) assess evidence in published literature on early life stress and major depressive disorders in adulthood, as well as correlate the DNA methylation profile on these conditions, (b) quantitatively synthesize the results of these published literature using random-effect meta-analysis procedure . . .

     

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