Aberrant expression of transglutaminase 2 in pancreas and thymus of nod mice underscores the importance of deamidation in neoantigen generation

HIGHLIGHTS

• who: A&yicy from the University of Su00e3o Paulo, Brazil have published the research work: Aberrant expression of transglutaminase 2 in pancreas and thymus of NOD mice underscores the importance of deamidation in neoantigen generation, in the Journal: (JOURNAL)
• what: The authors report on the aberrant expression and regulation of TGM2, one of the enzymes responsible for deamidation, in the pancreas and thymus of NOD mice. The authors demonstrate that TGM2 expression is induced by the inflammatory cytokines IL1b and IFNg in a synergistic manner and that murine pancreatic islets of NOD mice have higher . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.