Aberrant hypomethylation at imprinted differentially methylated regions is involved in biparental placental mesenchymal dysplasia

HIGHLIGHTS

  • who: Saori Aoki from the Division of Molecular Genetics and Epigenetics, Department of Biomolecular Sciences, Faculty of Medicine, Saga University, Saga, u20118501, Japan have published the article: Aberrant hypomethylation at imprinted differentially methylated regions is involved in biparental placental mesenchymal dysplasia, in the Journal: (JOURNAL)
  • what: The authors screened the genotypes of placental specimens obtained from 26 patients with PMD to investigate the frequency of biparental PMD. In the biparental-PMD and biparental-normal specimens, the authors focused on identifying the DMRs that were most frequently affected. NAP1L5 and WRB were also frequently aberrantly hypomethylated . . .

     

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