Aberrant induction of p19arf-mediated cellular senescence contributes to neurodevelopmental defects

HIGHLIGHTS

  • who: Muriel Rhinn and colleagues from the France France have published the research work: Aberrant induction of p19Arf-mediated cellular senescence contributes to neurodevelopmental defects, in the Journal: (JOURNAL) of June/14,/2022
  • what: While abnormal induction or chronic accumulation of senescent cells has been linked to many adult and age-related diseases, the authors demonstrate here a causative role for senescence in neurodevelopmental defects. The authors demonstrate that induction of senescence in the NE cells correlates with a subsequent impairment in PLOS Biology | https://doi.org/10.1371/journal.pbio . In support of this . . .

     

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