Ablation of the mir-465 cluster causes a skewed sex ratio in mice

HIGHLIGHTS

  • who: Zhuqing Wang from the Department of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV, United States, The have published the paper: Ablation of the miR-465 Cluster Causes a Skewed Sex Ratio in Mice, in the Journal: (JOURNAL)
  • what: The authors report that the miR-465 cluster miRNAs are also abundantly expressed in the developing placenta, and ablation of the miR-465 cluster does not affect fertility but causes a skewed sex ratio favoring males due to selective degradation of the female placenta during early embryonic development. While sexual . . .

     

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