Absence of uptake and prion-like spreading of alpha-synuclein and tau after intravitreal injection of preformed fibrils

HIGHLIGHTS

• who: Lies De Groef from the Laboratory Neural Circuit Development and Regeneration, Department of Biology, KU Leuven, Leuven, Belgium, France Case Western Reserve University have published the research: Absence of Uptake and Prion-Like Spreading of Alpha-Synuclein and Tau After Intravitreal Injection of Preformed Fibrils, in the Journal: (JOURNAL)
• what: The authors aimed to use the eye as a convenient entry route to the CNS, to investigate the uptake and spreading of α-syn and tau preformed fibrils (PFFs). While the α-syn and tau strains used in this study have been proven to induce seeding . . .
  

   

  

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