Accelerated amyloid angiopathy and related vascular alterations in a mixed murine model of alzheimer´s disease and type two diabetes

HIGHLIGHTS

  • who: Maria Vargas-Soria from the Division of PhysiologySchool of Medicine, University of Cadiz, Cadiz, Spain have published the research: Accelerated amyloid angiopathy and related vascular alterations in a mixed murine model of Alzheimeru00b4s disease and type two diabetes, in the Journal: (JOURNAL)
  • what: Limitations of this study include the use of isoflurane anesthesia, which affects vessel function.
  • how: Likewise the data are also in accordance with previous studies reporting that vasodilatation is compromised in aged AD mice .
  • future: Studies are needed to understand the link between APOE and T2D.
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