Accepted manuscript

HIGHLIGHTS

  • who: Karthik R from the State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China have published the research work: Accepted Manuscript, in the Journal: (JOURNAL)
  • what: The authors have shown that the lysosomal translocation of AXIN plays a dominant role to the lysosome to dissociate mTORC1 with a secondary mechanism involving AMPK phosphorylation of TSC2 and Raptor.

SUMMARY

    The authors found that the half-life of mTORC1, as determined by the time duration of glucose starvation required for . . .

     

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