HIGHLIGHTS
- who: Harikrishnan k from the Fudan University, Shanghai, China have published the research work: Accepted Manuscript, in the Journal: (JOURNAL)
SUMMARY
More recent studies discovered that Integrator is enriched in the proximity of gene promoters and can associate with paused Pol II bound by DSIF and NELF (Stadelmayer et_al, 2014; Yamamoto et_al, 2014) to trigger PTT and repress gene activity (Huang et_al, 2020). At the interface-IV, the exposed end of the INTS6 β-barrel domain contacts the HEAT domain of NELF-B, consistent with the known interaction between Integrator and NELF (Stadelmayer et_al . . .
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