Accounting for overlapping annotations in genomic prediction models of complex traits

HIGHLIGHTS

  • who: Fanny Mollandin from the Universitu00e9 Paris-Saclay, Allu00e9e de France have published the research work: Accounting for overlapping annotations in genomic prediction models of complex traits, in the Journal: (JOURNAL)
  • what: The authors propose two novel Bayesian approaches to account for multi-annotated markers through a cumulative (BayesRC+) or preferential (BayesRCu03c0 ) model of the contribution of multiple annotation categories. The authors explore several strategies for constructing annotations from a public database highlighting the importance of careful consideration of this step. Depending on the context, choice of annotations, and desired interpretation of multiannotated SNPs, in . . .

     

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