Accumulation of polychlorinated biphenyls in adipocytes: selective targeting to lipid droplets and role of caveolin-1

HIGHLIGHTS

  • who: Sophie Bourez and colleagues from the (UNIVERSITY) have published the Article: Accumulation of Polychlorinated Biphenyls in Adipocytes: Selective Targeting to Lipid Droplets and Role of Caveolin-1, in the Journal: (JOURNAL) of February/20,/2012
  • what: The authors show that 2 4 49-trichlorobiphenyl (PCB-28) 2 39 4 49 5-pentachlorobiphenyl (PCB-118) and 2 29 4 49 5 59-hexachlorobiphenyl (PCB-153) congeners rapidly and extensively accumulate in 3T3-L1 or mouse embryonic fibroblast (MEF) derived cultured adipocytes. By subcellular fractionation of primary adipocytes the authors demonstrate that these pollutants were almost . . .

     

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