Accurate genome-wide genotyping from archival tissue to explore the contribution of common genetic variants to pre-cancer outcomes

HIGHLIGHTS

  • who: Daniela Nachmanson from the Moores Center, University of California San Diego, Health Science Drive, San Diego, CA, USA have published the paper: Accurate genome-wide genotyping from archival tissue to explore the contribution of common genetic variants to pre-cancer outcomes, in the Journal: (JOURNAL)
  • what: The authors evaluate the validity of repurposing archival tissue specimens for germline genetic studies. The authors report that archival tissue DNA profiled with lc-WGS resulted in a reliable PRS estimate in an individual and preserved relative ranks in a cohort enabling studies such as the use case . . .

     

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