Accurate sequence variant genotyping in cattle using variation-aware genome graphs

HIGHLIGHTS

  • who: Danang Crysnanto from the (UNIVERSITY) have published the research: Accurate sequence variant genotyping in cattle using variation-aware genome graphs, in the Journal: (JOURNAL)
  • what: The authors compared sequence variant discovery and genotyping from a variation-aware genome graph using Graphtyper to two state-of-the-art methods (GATK and SAMtools) that rely on linear reference genomes from 49 Original Braunvieh cattle. Considering that the quality of the truth/training sets has a strong impact on the capabilities of VQSR (Additional file 6) and that high-confidence variants are currently not publicly available for . . .

     

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