Ace2-binding exposes the sars- cov-2 fusion peptide to broadly neutralizing coronavirus antibodies

HIGHLIGHTS

• who: ETH Library and collaborators from the InstitutUniversity of Washington, Seattle, WA, USA have published the research work: ACE2-binding exposes the SARS- CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies, in the Journal: (JOURNAL) of 12/08/2022
• what: These broadly reactive mAbs, which are the focus of the present study, were isolated from convalescent or vaccinated individuals, used different V genes (except for C13B8 and C13A7, which are clonally related), and displayed a high load of somatic mutations (7 to 14% in VH, 2 to 8% in VL at the nucleotide level . . .
  

   

  

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