HIGHLIGHTS
- who: Si Hyun Lee et al. from the Department of Physiology, College of Medicine, Hallym University, Chuncheon, Republic of Korea have published the article: Acid Sphingomyelinase Inhibitor, Imipramine, Reduces Hippocampal Neuronal Death after Traumatic Brain Injury, in the Journal: (JOURNAL)
- what: Based on the results of this study the authors confirmed that significantly reduced ceramide formation dendritic loss oxidative stress and neuronal death in the group compared with the TBI-vehicle group. The authors investigated whether imipramine, as an ASMase inhibitor, can reduce ceramide formation and, thus, prevent TBI-induced neuronal death in rats. The . . .
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