Ackr3 expression on diffuse large b cell lymphoma is required for tumor spreading and tissue infiltration

HIGHLIGHTS

  • who: Top from the Institute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona, Switzerland Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland have published the research: ACKR3 expression on diffuse large B cell lymphoma is required for tumor spreading and tissue infiltration, in the Journal: (JOURNAL)
  • how: Previous data showed that systemic inhibition of CXCL12 scavenging by ACKR3 with small_molecule antagonists such as CCX754 and CCX771 caused markedly increased CXCL12 serum levels .

SUMMARY

    The importance of the chemokine system for orchestrating the homeostatic and inflammatory leucocyte . . .

     

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