HIGHLIGHTS
- who: Jake S. O’Donnell from the (UNIVERSITY) have published the paper: Acquired resistance to anti-PD1 therapy: checkmate to checkpoint blockade?, in the Journal: (JOURNAL)
- what: From this study demonstrated that mutations which affected the sensitivity of tumor cells to T-cell-derived interferons, and mutations limiting tumor-cell antigen presentation, could cause acquired resistance.
SUMMARY
O'Donnell et_al Genome Medicine 8:111 DOI 10.1186/s13073-016-0365-1 COMMENT Open Access Acquired resistance to anti-PD1 therapy: checkmate to checkpoint blockade? A recent study sought to identify mutations . . .
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